Spontaneous pneumothorax after intensive chemotherapy in endometrial cancer: A rare complication

• Main Authors: Jen-Ruei Chen, Yuh-Cheng Yang
• Format: Article
• Language: English
• Published: Elsevier 2014-06-01
• Series: Taiwanese Journal of Obstetrics & Gynecology
• Subjects: carboplatin; endometrial cancer; paclitaxel; pulmonary metastases; spontaneous pneumothorax
• Online Access: http://www.sciencedirect.com/science/article/pii/S1028455914000825

Objective: Endometrial cancer with hematogenous metastases can be treated with chemotherapy. We present a case of spontaneous pneumothorax that occurred when a solitary pulmonary endometrial metastatic lesion was treated with paclitaxel plus carboplatin. Case report: A 38-year-old female had stage II endometrial endometrioid adenocarcinoma. Solitary bilateral pulmonary metastases developed after primary treatment. Complete remission accompanied by a right spontaneous pneumothorax occurred during chemotherapy with paclitaxel plus carboplatin. Conclusion: Rapid shrinkage of a pulmonary space-occupying tumor sometimes causes rare but life-threatening spontaneous pneumothoraces. We report the first case of a spontaneous pneumothorax after using paclitaxel plus carboplatin in the treatment of endometrial cancer.