In Vitro and In Silico Insights into sEH Inhibitors with Amide-Scaffold from the Leaves of Capsicum chinense Jacq.

Two compounds termed 1 and 2 were isolated from the leaves of Capsicum chinense using column chromatography. Their structures were identified as amide scaffolds by analyzing spectroscopic signals. Compounds 1 and 2 have been confirmed to be competitive soluble epoxide hydrolase (sEH) inhibitors that...

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Bibliographic Details
Main Authors: Jang Hoon Kim, Yeong Deuk Jo, Hyo-Young Kim, Bo-Ram Kim, Bomi Nam
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:Computational and Structural Biotechnology Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037018301417