Congenital candidiasis

• Main Authors: Chintaginjala Aruna, Kolalapudi Seetharam
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2014-01-01
• Series: Indian Dermatology Online Journal
• Subjects: Candidiasis; congenital; fluconazole; pustular eruption
• Online Access: http://www.idoj.in/article.asp?issn=2229-5178;year=2014;volume=5;issue=5;spage=44;epage=47;aulast=Aruna

Congenital candidiasis (CC) is a rare disease with less than 100 cases being reported in the literature. It presents within six days of life with manifestations ranging from localized skin disease to systemic involvement in the form of respiratory distress, sepsis, and death. We report a neonate who presented with diffuse pustular eruption on erythematous background involving face, trunk, and palms within 24 h after birth. Candida albicans was identified in 10% potassium hydroxide (KOH) smear and culture from the pustules. Intravenous fluconazole and topical ketoconazole were given and the condition improved completely in two weeks. CC is rare and needs to be differentiated from other conditions presenting with pustular lesions at birth in order to avoid complications. Early diagnosis and prompt treatment of this condition is important as untreated cases carry a mortality rate of 8-40%.