Immunomodulatory effects of thalidomide in an experimental brain death liver donor model

Immunomodulatory effects of thalidomide in an experimental brain death liver donor model

Abstract Brain death is characterized by a generalized inflammatory response that results in multiorgan damage. This process is mainly mediated through cytokines, which amplify graft immunogenicity. We investigated the immunological response in a brain death liver donor model and analysed the effect...

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Main Authors: Alexandre Chagas Santana, Wellington Andraus, Filipe Miranda Oliveira Silva, Humberto Dellê, Rafael Pepineli, Edvaldo Leal de Moraes, Cristoforo Scavone, Larissa de Sá Lima, Sabrina Degaspari, Sergio Brasil, Davi Jorge Fontoura Solla, Liliane Moreira Ruiz, Karina Andrighetti de Oliveira-Braga, Natalia Aparecida Nepomuceno, Paulo Manuel Pêgo-Fernandes, Stefan Gunther Tullius, Eberval Gadelha Figueiredo
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-98538-z

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