Human serum promotes Candida albicans biofilm growth and virulence gene expression on silicone biomaterial.

Human serum promotes Candida albicans biofilm growth and virulence gene expression on silicone biomaterial.

OBJECTIVES: Systemic candidal infections are a common problem in hospitalized patients due to central venous catheters fabricated using silicone biomaterial (SB). We therefore evaluated the effect of human serum on C. albicans biofilm morphology, growth, and the expression of virulence-related genes...

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Bibliographic Details
Main Authors: Yuthika Hemamala Samaranayake, Becky P K Cheung, Joyce Y Y Yau, Shadow K W Yeung, Lakshman P Samaranayake
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3660551?pdf=render

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