Improving power of genome-wide association studies with weighted false discovery rate control and prioritized subset analysis.

The issue of large-scale testing has caught much attention with the advent of high-throughput technologies. In genomic studies, researchers are often confronted with a large number of tests. To make simultaneous inference for the many tests, the false discovery rate (FDR) control provides a practica...

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Bibliographic Details
Main Authors: Wan-Yu Lin, Wen-Chung Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3322139?pdf=render