Value of CT-guided percutaneous needle biopsy of bone in the diagnosis of lymphomas based on PET/CT results

• Main Authors: Zhiwei Wang, Haifeng Shi, Xiaobo Zhang, Jie Pan, Zhengyu Jin
• Format: Article
• Language: English
• Published: BMC 2019-06-01
• Series: Cancer Imaging
• Subjects: Needle biopsy; Bone; Lymphoma; PET/CT
• Online Access: http://link.springer.com/article/10.1186/s40644-019-0230-8

Abstract Background To evaluate the value of CT-guided percutaneous needle biopsy of bone in the diagnosis of lymphomas based on PET/CT results. Methods A retrospective analysis of the records of all patients with percutaneous bone biopsies based on PET/CT results and a final diagnosis of lymphoma between January 2012 and August 2017 was performed. Thirty-one patients were included in this study. The success and complication rates were assessed. Results The mean age of the 31 patients was 46.6 ± 21.2 years, and there were 16 men and 15 women. A definite diagnosis and accurate histological subtype were obtained in 26 patients, for a success rate of 84%. The most common subtype was diffuse large B cell lymphoma (n = 18). The remaining subtypes included three cases of marginal-zone lymphoma, two cases of follicular lymphoma, one case of Hodgkin’s lymphoma, one case of peripheral T cell lymphoma, and one case of B cell lymphoblastic lymphoma. No serious complications occurred in any of the patients. Conclusions CT-guided needle biopsy based on PET/CT results is a reliable means of diagnosing and classifying lymphomas.