The hedgehog signal induced modulation of bone morphogenetic protein signaling: an essential signaling relay for urinary tract morphogenesis.

Congenital diseases of the urinary tract are frequently observed in infants. Such diseases present a number of developmental anomalies such as hydroureter and hydronephrosis. Although some genetically-modified mouse models of growth factor signaling genes reproduce urinary phenotypes, the pathogenic...

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Bibliographic Details
Main Authors: Ryuma Haraguchi, Daisuke Matsumaru, Naomi Nakagata, Shinichi Miyagawa, Kentaro Suzuki, Sohei Kitazawa, Gen Yamada
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3408458?pdf=render