Numerical simulation of patient-specific endovascular stenting and coiling for intracranial aneurysm surgical planning

• Main Authors: Xiaochang Leng, Yang Wang, Jing Xu, Yeqing Jiang, Xiaolong Zhang, Jianping Xiang
• Format: Article
• Language: English
• Published: BMC 2018-07-01
• Series: Journal of Translational Medicine
• Subjects: Stent; Coil; Aneurysm; Nitinol; FEM; CFD
• Online Access: http://link.springer.com/article/10.1186/s12967-018-1573-9

Abstract Background In this study, we develop reliable and practical virtual coiling and stenting methods for intracranial aneurysm surgical planning. Since the purpose of deploying coils and stents is to provide device geometries for subsequent accurate post-treatment computational fluid dynamics analysis, we do not need to accurately capture all the details such as the stress and force distribution for the devices and vessel walls. Our philosophy for developing these methods is to balance accuracy and practicality. Methods We consider the mechanical properties of the devices and recapitulate the clinical practice using a finite element method (FEM) approach. At the same time, we apply some simplifications for FEM modeling to make our methods efficient. For the virtual coiling, the coils are modeled as 3D Euler–Bernoulli beam elements, which is computationally efficient and provides good geometry representation. During the stent deployment process, the stent–catheter system is transformed according to the centerline of the parent vessel since the final configuration of the stent is not dependent of the deployment history. The aneurysm and vessel walls are assumed to be rigid and are fully constrained during the simulation. All stent–catheter system and coil–catheter system are prepared and packaged as a library which contains all types of stents, coils and catheters, which improves the efficiency of surgical planning process. Results The stent was delivered to the suitable position during the clinical treatment, achieving good expansion and apposition of the stent to the arterial wall. The coil was deployed into the aneurysm sac and deformed to different shapes because of the stored strain energy during coil package process and the direction of the microcatheter. Conclusions The method which we develop here could become surgical planning for intracranial aneurysm treatment in the clinical workflow.