Applications of Melatonin in Female Reproduction in the Context of Oxidative Stress

Applications of Melatonin in Female Reproduction in the Context of Oxidative Stress

Oxidative stress has been recognized as one of the causal mediators of female infertility by affecting the oocyte quality and early embryo development. Improving oxidative stress is essential for reproductive health. Melatonin, a self-secreted antioxidant, has a wide range of effects by improving mi...

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Main Authors: Yonghui Jiang, Huangcong Shi, Yue Liu, Shigang Zhao, Han Zhao
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2021/6668365
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spelling doaj-c35854ae503141c39e2b36e3986adc672021-08-09T00:00:26ZengHindawi LimitedOxidative Medicine and Cellular Longevity1942-09942021-01-01202110.1155/2021/6668365Applications of Melatonin in Female Reproduction in the Context of Oxidative StressYonghui Jiang0Huangcong Shi1Yue Liu2Shigang Zhao3Han Zhao4Center for Reproductive MedicineCenter for Reproductive MedicineCenter for Reproductive MedicineCenter for Reproductive MedicineCenter for Reproductive MedicineOxidative stress has been recognized as one of the causal mediators of female infertility by affecting the oocyte quality and early embryo development. Improving oxidative stress is essential for reproductive health. Melatonin, a self-secreted antioxidant, has a wide range of effects by improving mitochondrial function and reducing the damage of reactive oxygen species (ROS). This minireview illustrates the applications of melatonin in reproduction from four aspects: physiological ovarian aging, vitrification freezing, in vitro maturation (IVM), and oxidative stress homeostasis imbalance associated with polycystic ovary syndrome (PCOS), emphasising the role of melatonin in improving the quality of oocytes in assisted reproduction and other adverse conditions.http://dx.doi.org/10.1155/2021/6668365
collection DOAJ
language English
format Article
sources DOAJ
author Yonghui Jiang
Huangcong Shi
Yue Liu
Shigang Zhao
Han Zhao
spellingShingle Yonghui Jiang
Huangcong Shi
Yue Liu
Shigang Zhao
Han Zhao
Applications of Melatonin in Female Reproduction in the Context of Oxidative Stress
Oxidative Medicine and Cellular Longevity
author_facet Yonghui Jiang
Huangcong Shi
Yue Liu
Shigang Zhao
Han Zhao
author_sort Yonghui Jiang
title Applications of Melatonin in Female Reproduction in the Context of Oxidative Stress
title_short Applications of Melatonin in Female Reproduction in the Context of Oxidative Stress
title_full Applications of Melatonin in Female Reproduction in the Context of Oxidative Stress
title_fullStr Applications of Melatonin in Female Reproduction in the Context of Oxidative Stress
title_full_unstemmed Applications of Melatonin in Female Reproduction in the Context of Oxidative Stress
title_sort applications of melatonin in female reproduction in the context of oxidative stress
publisher Hindawi Limited
series Oxidative Medicine and Cellular Longevity
issn 1942-0994
publishDate 2021-01-01
description Oxidative stress has been recognized as one of the causal mediators of female infertility by affecting the oocyte quality and early embryo development. Improving oxidative stress is essential for reproductive health. Melatonin, a self-secreted antioxidant, has a wide range of effects by improving mitochondrial function and reducing the damage of reactive oxygen species (ROS). This minireview illustrates the applications of melatonin in reproduction from four aspects: physiological ovarian aging, vitrification freezing, in vitro maturation (IVM), and oxidative stress homeostasis imbalance associated with polycystic ovary syndrome (PCOS), emphasising the role of melatonin in improving the quality of oocytes in assisted reproduction and other adverse conditions.
url http://dx.doi.org/10.1155/2021/6668365
work_keys_str_mv AT yonghuijiang applicationsofmelatonininfemalereproductioninthecontextofoxidativestress
AT huangcongshi applicationsofmelatonininfemalereproductioninthecontextofoxidativestress
AT yueliu applicationsofmelatonininfemalereproductioninthecontextofoxidativestress
AT shigangzhao applicationsofmelatonininfemalereproductioninthecontextofoxidativestress
AT hanzhao applicationsofmelatonininfemalereproductioninthecontextofoxidativestress
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