Co-Administration of Aluminium Hydroxide Nanoparticles and Protective Antigen Domain 4 Encapsulated Non-Ionic Surfactant Vesicles Show Enhanced Immune Response and Superior Protection against Anthrax

Co-Administration of Aluminium Hydroxide Nanoparticles and Protective Antigen Domain 4 Encapsulated Non-Ionic Surfactant Vesicles Show Enhanced Immune Response and Superior Protection against Anthrax

Aluminium salts have been the adjuvant of choice in more than 100 licensed vaccines. Here, we have studied the synergistic effect of aluminium hydroxide nanoparticles (AH np) and non-ionic surfactant-based vesicles (NISV) in modulating the immune response against protective antigen domain 4 (D4) of...

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Bibliographic Details
Main Authors: Himanshu Gogoi, Rajesh Mani, Anshu Malik, Parveen Sehrawat, Rakesh Bhatnagar
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Vaccines
Subjects:
<i>Bacillus anthracis</i>
protective antigen domain 4
aluminium hydroxide nanoparticles
non-ionic surfactant vesicles
nanoformulation
Online Access:https://www.mdpi.com/2076-393X/8/4/571

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