On the reproduction number and the optimal control of infectious diseases in a heterogenous population

Abstract The effect of infectious diseases cannot be overemphasised. The continuing surfacing of the infectious diseases gives the stakeholders a great concern. In this paper, the nature of the spread of Ebola virus outbreak in West Africa in 2014 is studied. We develop a model that analyses the spr...

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Main Authors: A. U. Chukwu, J. A. Akinyemi, M. O. Adeniyi, S. O. Salawu
Format: Article
Language:English
Published: SpringerOpen 2020-10-01
Series:Advances in Difference Equations
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13662-020-03050-9
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spelling doaj-c3480fe413cb4121be231eaebd0f82762020-11-25T03:52:47ZengSpringerOpenAdvances in Difference Equations1687-18472020-10-012020111410.1186/s13662-020-03050-9On the reproduction number and the optimal control of infectious diseases in a heterogenous populationA. U. Chukwu0J. A. Akinyemi1M. O. Adeniyi2S. O. Salawu3Department of Statistics, University of IbadanDepartment of Maths/Statistics, Lagos State PolytechnicDepartment of Maths/Statistics, Lagos State PolytechnicDepartment of Mathematics, Landmark UniversityAbstract The effect of infectious diseases cannot be overemphasised. The continuing surfacing of the infectious diseases gives the stakeholders a great concern. In this paper, the nature of the spread of Ebola virus outbreak in West Africa in 2014 is studied. We develop a model that analyses the spread of infectious diseases, and the reproduction number is determined by using the next generation matrix method. Finally, the effects of treatment of the infected individuals and vaccination of the susceptible population as the control strategies are looked into. The optimal control system showed that the combination of the two strategies proved more effective.http://link.springer.com/article/10.1186/s13662-020-03050-9Reproduction numberOptimal controlHeterogeneous populationInfectious diseases
collection DOAJ
language English
format Article
sources DOAJ
author A. U. Chukwu
J. A. Akinyemi
M. O. Adeniyi
S. O. Salawu
spellingShingle A. U. Chukwu
J. A. Akinyemi
M. O. Adeniyi
S. O. Salawu
On the reproduction number and the optimal control of infectious diseases in a heterogenous population
Advances in Difference Equations
Reproduction number
Optimal control
Heterogeneous population
Infectious diseases
author_facet A. U. Chukwu
J. A. Akinyemi
M. O. Adeniyi
S. O. Salawu
author_sort A. U. Chukwu
title On the reproduction number and the optimal control of infectious diseases in a heterogenous population
title_short On the reproduction number and the optimal control of infectious diseases in a heterogenous population
title_full On the reproduction number and the optimal control of infectious diseases in a heterogenous population
title_fullStr On the reproduction number and the optimal control of infectious diseases in a heterogenous population
title_full_unstemmed On the reproduction number and the optimal control of infectious diseases in a heterogenous population
title_sort on the reproduction number and the optimal control of infectious diseases in a heterogenous population
publisher SpringerOpen
series Advances in Difference Equations
issn 1687-1847
publishDate 2020-10-01
description Abstract The effect of infectious diseases cannot be overemphasised. The continuing surfacing of the infectious diseases gives the stakeholders a great concern. In this paper, the nature of the spread of Ebola virus outbreak in West Africa in 2014 is studied. We develop a model that analyses the spread of infectious diseases, and the reproduction number is determined by using the next generation matrix method. Finally, the effects of treatment of the infected individuals and vaccination of the susceptible population as the control strategies are looked into. The optimal control system showed that the combination of the two strategies proved more effective.
topic Reproduction number
Optimal control
Heterogeneous population
Infectious diseases
url http://link.springer.com/article/10.1186/s13662-020-03050-9
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