Laboratory tests and clinical significance of anti-3-hydroxy-3-methylglutaryl coenzyme A reductase antibody

<p>Anti-3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) antibody is a newly recognized autoantibody, which is associated with the use of statins and is considered as an immunological marker of necrotizing autoimmune myopathy (NAM). This article summarizes the discovery, laboratory t...

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Main Authors: Jing-jing LUO, Feng GAO, Jie-xi WEN, Hong-jun HAO, Jing GUO, Yi-ning HUANG
Format: Article
Language:English
Published: Tianjin Huanhu Hospital 2016-09-01
Series:Chinese Journal of Contemporary Neurology and Neurosurgery
Subjects:
Online Access:http://www.cjcnn.org/index.php/cjcnn/article/view/1455
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spelling doaj-c347cc5be03848d696cd56923a57549c2020-11-25T02:42:29ZengTianjin Huanhu HospitalChinese Journal of Contemporary Neurology and Neurosurgery1672-67312016-09-011695735751433Laboratory tests and clinical significance of anti-3-hydroxy-3-methylglutaryl coenzyme A reductase antibodyJing-jing LUO0Feng GAO1Jie-xi WEN2Hong-jun HAO3Jing GUO4Yi-ning HUANG5Department of Neurology, Peking University First Hospital, Beijing 100034, ChinaDepartment of Neurology, Peking University First Hospital, Beijing 100034, ChinaDepartment of Neurology, Peking University First Hospital, Beijing 100034, ChinaDepartment of Neurology, Peking University First Hospital, Beijing 100034, ChinaDepartment of Neurology, Peking University First Hospital, Beijing 100034, ChinaDepartment of Neurology, Peking University First Hospital, Beijing 100034, China<p>Anti-3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) antibody is a newly recognized autoantibody, which is associated with the use of statins and is considered as an immunological marker of necrotizing autoimmune myopathy (NAM). This article summarizes the discovery, laboratory tests and clinical significance of anti-HMGCR antibody.</p><p> </p><p><strong>DOI: </strong>10.3969/j.issn.1672-6731.2016.09.005</p>http://www.cjcnn.org/index.php/cjcnn/article/view/1455Hydroxymethylglutaryl CoA reductasesImmunoassayAntilipemic agentsReview
collection DOAJ
language English
format Article
sources DOAJ
author Jing-jing LUO
Feng GAO
Jie-xi WEN
Hong-jun HAO
Jing GUO
Yi-ning HUANG
spellingShingle Jing-jing LUO
Feng GAO
Jie-xi WEN
Hong-jun HAO
Jing GUO
Yi-ning HUANG
Laboratory tests and clinical significance of anti-3-hydroxy-3-methylglutaryl coenzyme A reductase antibody
Chinese Journal of Contemporary Neurology and Neurosurgery
Hydroxymethylglutaryl CoA reductases
Immunoassay
Antilipemic agents
Review
author_facet Jing-jing LUO
Feng GAO
Jie-xi WEN
Hong-jun HAO
Jing GUO
Yi-ning HUANG
author_sort Jing-jing LUO
title Laboratory tests and clinical significance of anti-3-hydroxy-3-methylglutaryl coenzyme A reductase antibody
title_short Laboratory tests and clinical significance of anti-3-hydroxy-3-methylglutaryl coenzyme A reductase antibody
title_full Laboratory tests and clinical significance of anti-3-hydroxy-3-methylglutaryl coenzyme A reductase antibody
title_fullStr Laboratory tests and clinical significance of anti-3-hydroxy-3-methylglutaryl coenzyme A reductase antibody
title_full_unstemmed Laboratory tests and clinical significance of anti-3-hydroxy-3-methylglutaryl coenzyme A reductase antibody
title_sort laboratory tests and clinical significance of anti-3-hydroxy-3-methylglutaryl coenzyme a reductase antibody
publisher Tianjin Huanhu Hospital
series Chinese Journal of Contemporary Neurology and Neurosurgery
issn 1672-6731
publishDate 2016-09-01
description <p>Anti-3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) antibody is a newly recognized autoantibody, which is associated with the use of statins and is considered as an immunological marker of necrotizing autoimmune myopathy (NAM). This article summarizes the discovery, laboratory tests and clinical significance of anti-HMGCR antibody.</p><p> </p><p><strong>DOI: </strong>10.3969/j.issn.1672-6731.2016.09.005</p>
topic Hydroxymethylglutaryl CoA reductases
Immunoassay
Antilipemic agents
Review
url http://www.cjcnn.org/index.php/cjcnn/article/view/1455
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