Inhibition of NADPH Oxidases Activity by Diphenyleneiodonium Chloride as a Mechanism of Senescence Induction in Human Cancer Cells

Inhibition of NADPH Oxidases Activity by Diphenyleneiodonium Chloride as a Mechanism of Senescence Induction in Human Cancer Cells

NADPH oxidases (NOX) are commonly expressed ROS-producing enzymes that participate in the regulation of many signaling pathways, which influence cell metabolism, survival, and proliferation. Due to their high expression in several different types of cancer it was postulated that NOX promote tumor pr...

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Bibliographic Details
Main Authors: Katarzyna Piszczatowska, Dorota Przybylska, Ewa Sikora, Grażyna Mosieniak
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Antioxidants
Subjects:
senescence
apoptosis
cancer
ROS
NADPH oxidases
DPI
Online Access:https://www.mdpi.com/2076-3921/9/12/1248

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