Immunogenetics of Small Ruminant Lentiviral Infections

Immunogenetics of Small Ruminant Lentiviral Infections

The small ruminant lentiviruses (SRLV) include the caprine arthritis encephalitis virus (CAEV) and the Maedi-Visna virus (MVV). Both of these viruses limit production and can be a major source of economic loss to producers. Little is known about how the immune system recognizes and responds to SRLVs...

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Main Authors: Nancy Stonos, Sarah K. Wootton, Niel Karrow
Format: Article
Language:English
Published: MDPI AG 2014-08-01
Series:Viruses
Subjects:
SRLV
immune response
genetic selection
Online Access:http://www.mdpi.com/1999-4915/6/8/3311
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spelling doaj-c320c08b6adc416d94bba60c24c0dcae2020-11-24T22:53:40ZengMDPI AGViruses1999-49152014-08-01683311333310.3390/v6083311v6083311Immunogenetics of Small Ruminant Lentiviral InfectionsNancy Stonos0Sarah K. Wootton1Niel Karrow2Centre for the Genetic Improvement of Livestock, Department of Animal and Poultry Science, University of Guelph, Guelph, ON N1G 2W1, CanadaDepartment of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1, CanadaCentre for the Genetic Improvement of Livestock, Department of Animal and Poultry Science, University of Guelph, Guelph, ON N1G 2W1, CanadaThe small ruminant lentiviruses (SRLV) include the caprine arthritis encephalitis virus (CAEV) and the Maedi-Visna virus (MVV). Both of these viruses limit production and can be a major source of economic loss to producers. Little is known about how the immune system recognizes and responds to SRLVs, but due to similarities with the human immunodeficiency virus (HIV), HIV research can shed light on the possible immune mechanisms that control or lead to disease progression. This review will focus on the host immune response to HIV-1 and SRLV, and will discuss the possibility of breeding for enhanced SRLV disease resistance.http://www.mdpi.com/1999-4915/6/8/3311SRLVimmune responsegenetic selection
collection DOAJ
language English
format Article
sources DOAJ
author Nancy Stonos
Sarah K. Wootton
Niel Karrow
spellingShingle Nancy Stonos
Sarah K. Wootton
Niel Karrow
Immunogenetics of Small Ruminant Lentiviral Infections
Viruses
SRLV
immune response
genetic selection
author_facet Nancy Stonos
Sarah K. Wootton
Niel Karrow
author_sort Nancy Stonos
title Immunogenetics of Small Ruminant Lentiviral Infections
title_short Immunogenetics of Small Ruminant Lentiviral Infections
title_full Immunogenetics of Small Ruminant Lentiviral Infections
title_fullStr Immunogenetics of Small Ruminant Lentiviral Infections
title_full_unstemmed Immunogenetics of Small Ruminant Lentiviral Infections
title_sort immunogenetics of small ruminant lentiviral infections
publisher MDPI AG
series Viruses
issn 1999-4915
publishDate 2014-08-01
description The small ruminant lentiviruses (SRLV) include the caprine arthritis encephalitis virus (CAEV) and the Maedi-Visna virus (MVV). Both of these viruses limit production and can be a major source of economic loss to producers. Little is known about how the immune system recognizes and responds to SRLVs, but due to similarities with the human immunodeficiency virus (HIV), HIV research can shed light on the possible immune mechanisms that control or lead to disease progression. This review will focus on the host immune response to HIV-1 and SRLV, and will discuss the possibility of breeding for enhanced SRLV disease resistance.
topic SRLV
immune response
genetic selection
url http://www.mdpi.com/1999-4915/6/8/3311
work_keys_str_mv AT nancystonos immunogeneticsofsmallruminantlentiviralinfections
AT sarahkwootton immunogeneticsofsmallruminantlentiviralinfections
AT nielkarrow immunogeneticsofsmallruminantlentiviralinfections
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