An Evaluation of the Use of Serum 7-alpha-hydroxycholestenone as a Diagnostic Test of Bile Acid Malabsorption Causing Watery Diarrhea

An Evaluation of the Use of Serum 7-alpha-hydroxycholestenone as a Diagnostic Test of Bile Acid Malabsorption Causing Watery Diarrhea

BACKGROUND: Bile acid malabsorption (BAM) is a recognized cause of watery diarrhea, often diagnosed empirically based on clinical response to cholestyramine. The radionuclide selenium-labelled homocholic acid-taurine whole body retention test is expensive, labour intensive and of limited availabilit...

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Main Authors: W Gordon Brydon, Pearl Culbert, Kathleen Kingstone, Ann Jarvie, Marietta Iacucci, Merel Tenhage, Subrata Ghosh
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2011/701287
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spelling doaj-c2f9c139e4c142ab86642579c44f34dd2020-11-25T00:14:38ZengHindawi LimitedCanadian Journal of Gastroenterology0835-79002011-01-0125631932310.1155/2011/701287An Evaluation of the Use of Serum 7-alpha-hydroxycholestenone as a Diagnostic Test of Bile Acid Malabsorption Causing Watery DiarrheaW Gordon Brydon0Pearl Culbert1Kathleen Kingstone2Ann Jarvie3Marietta Iacucci4Merel Tenhage5Subrata Ghosh6Departments of Clinical Biochemistry and Gastroenterology, Western General Hospital, Edinburgh, ScotlandDepartments of Clinical Biochemistry and Gastroenterology, Western General Hospital, Edinburgh, ScotlandDepartments of Clinical Biochemistry and Gastroenterology, Western General Hospital, Edinburgh, ScotlandDepartments of Clinical Biochemistry and Gastroenterology, Western General Hospital, Edinburgh, ScotlandHammersmith Hospital, Imperial College London, United KingdomNova College, The NetherlandsDivision of Gastroenterology, University of Calgary, Calgary, Alberta, CanadaBACKGROUND: Bile acid malabsorption (BAM) is a recognized cause of watery diarrhea, often diagnosed empirically based on clinical response to cholestyramine. The radionuclide selenium-labelled homocholic acid-taurine whole body retention test is expensive, labour intensive and of limited availability.http://dx.doi.org/10.1155/2011/701287
collection DOAJ
language English
format Article
sources DOAJ
author W Gordon Brydon
Pearl Culbert
Kathleen Kingstone
Ann Jarvie
Marietta Iacucci
Merel Tenhage
Subrata Ghosh
spellingShingle W Gordon Brydon
Pearl Culbert
Kathleen Kingstone
Ann Jarvie
Marietta Iacucci
Merel Tenhage
Subrata Ghosh
An Evaluation of the Use of Serum 7-alpha-hydroxycholestenone as a Diagnostic Test of Bile Acid Malabsorption Causing Watery Diarrhea
Canadian Journal of Gastroenterology
author_facet W Gordon Brydon
Pearl Culbert
Kathleen Kingstone
Ann Jarvie
Marietta Iacucci
Merel Tenhage
Subrata Ghosh
author_sort W Gordon Brydon
title An Evaluation of the Use of Serum 7-alpha-hydroxycholestenone as a Diagnostic Test of Bile Acid Malabsorption Causing Watery Diarrhea
title_short An Evaluation of the Use of Serum 7-alpha-hydroxycholestenone as a Diagnostic Test of Bile Acid Malabsorption Causing Watery Diarrhea
title_full An Evaluation of the Use of Serum 7-alpha-hydroxycholestenone as a Diagnostic Test of Bile Acid Malabsorption Causing Watery Diarrhea
title_fullStr An Evaluation of the Use of Serum 7-alpha-hydroxycholestenone as a Diagnostic Test of Bile Acid Malabsorption Causing Watery Diarrhea
title_full_unstemmed An Evaluation of the Use of Serum 7-alpha-hydroxycholestenone as a Diagnostic Test of Bile Acid Malabsorption Causing Watery Diarrhea
title_sort evaluation of the use of serum 7-alpha-hydroxycholestenone as a diagnostic test of bile acid malabsorption causing watery diarrhea
publisher Hindawi Limited
series Canadian Journal of Gastroenterology
issn 0835-7900
publishDate 2011-01-01
description BACKGROUND: Bile acid malabsorption (BAM) is a recognized cause of watery diarrhea, often diagnosed empirically based on clinical response to cholestyramine. The radionuclide selenium-labelled homocholic acid-taurine whole body retention test is expensive, labour intensive and of limited availability.
url http://dx.doi.org/10.1155/2011/701287
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