Towards Enhanced MRI Performance of Tumor-Specific Dimeric Phenylboronic Contrast Agents

It is known that phenylboronic acid (PBA) can target tumor tissues by binding to sialic acid, a substrate overexpressed by cancer cells. This capability has previously been explored in the design of targeting diagnostic probes such as Gd- and <sup>68</sup>Ga-DOTA-EN-PBA, two contrast age...

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Bibliographic Details
Main Authors: Jonathan Martinelli, Lorenzo Tei, Simonetta Geninatti Crich, Diego Alberti, Kristina Djanashvili
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/26/6/1730