Integrated TORC1 and PKA signaling control the temporal activation of glucose-induced gene expression in yeast

Integrated TORC1 and PKA signaling control the temporal activation of glucose-induced gene expression in yeast

Yeast cells respond to nutrients by altering expression of the protein synthesis genes and thus their growth rate. Here, the authors use microarrays to show that TORC1 controls gene expression during steady state growth while PKA speeds up expression changes when nutrient levels change.

Bibliographic Details
Main Authors: Joseph Kunkel, Xiangxia Luo, Andrew P. Capaldi
Format: Article
Language:English
Published: Nature Publishing Group 2019-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11540-y
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spelling doaj-c2f0f6643f4a4866a44a494c9713d2d72021-05-11T12:20:31ZengNature Publishing GroupNature Communications2041-17232019-08-0110111110.1038/s41467-019-11540-yIntegrated TORC1 and PKA signaling control the temporal activation of glucose-induced gene expression in yeastJoseph Kunkel0Xiangxia Luo1Andrew P. Capaldi2Department of Molecular and Cellular Biology, University of ArizonaDepartment of Molecular and Cellular Biology, University of ArizonaDepartment of Molecular and Cellular Biology, University of ArizonaYeast cells respond to nutrients by altering expression of the protein synthesis genes and thus their growth rate. Here, the authors use microarrays to show that TORC1 controls gene expression during steady state growth while PKA speeds up expression changes when nutrient levels change.https://doi.org/10.1038/s41467-019-11540-y
collection DOAJ
language English
format Article
sources DOAJ
author Joseph Kunkel
Xiangxia Luo
Andrew P. Capaldi
spellingShingle Joseph Kunkel
Xiangxia Luo
Andrew P. Capaldi
Integrated TORC1 and PKA signaling control the temporal activation of glucose-induced gene expression in yeast
Nature Communications
author_facet Joseph Kunkel
Xiangxia Luo
Andrew P. Capaldi
author_sort Joseph Kunkel
title Integrated TORC1 and PKA signaling control the temporal activation of glucose-induced gene expression in yeast
title_short Integrated TORC1 and PKA signaling control the temporal activation of glucose-induced gene expression in yeast
title_full Integrated TORC1 and PKA signaling control the temporal activation of glucose-induced gene expression in yeast
title_fullStr Integrated TORC1 and PKA signaling control the temporal activation of glucose-induced gene expression in yeast
title_full_unstemmed Integrated TORC1 and PKA signaling control the temporal activation of glucose-induced gene expression in yeast
title_sort integrated torc1 and pka signaling control the temporal activation of glucose-induced gene expression in yeast
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2019-08-01
description Yeast cells respond to nutrients by altering expression of the protein synthesis genes and thus their growth rate. Here, the authors use microarrays to show that TORC1 controls gene expression during steady state growth while PKA speeds up expression changes when nutrient levels change.
url https://doi.org/10.1038/s41467-019-11540-y
work_keys_str_mv AT josephkunkel integratedtorc1andpkasignalingcontrolthetemporalactivationofglucoseinducedgeneexpressioninyeast
AT xiangxialuo integratedtorc1andpkasignalingcontrolthetemporalactivationofglucoseinducedgeneexpressioninyeast
AT andrewpcapaldi integratedtorc1andpkasignalingcontrolthetemporalactivationofglucoseinducedgeneexpressioninyeast
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