Silencing of ASC in Cutaneous Squamous Cell Carcinoma.

Silencing of ASC in Cutaneous Squamous Cell Carcinoma.

Apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC) is an important adaptor protein for inflammasome activation, mediating the secretion of protumorigenic innate cytokines. However, ASC is also known to trigger apoptosis in tumor cells, acting as a tumor-suppressor...

Full description

Bibliographic Details
Main Authors: Katharina Meier, Stefan K Drexler, Franziska C Eberle, Karine Lefort, Amir S Yazdi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5074456?pdf=render

Similar Items

Similar Items