Current State of Dendritic Cell-Based Immunotherapy: Opportunities for in vitro Antigen Loading of Different DC Subsets?

Current State of Dendritic Cell-Based Immunotherapy: Opportunities for in vitro Antigen Loading of Different DC Subsets?

Dendritic cell (DC) based cancer immunotherapy aims at the activation of the immune system, and in particular tumor-specific cytotoxic T lymphocytes (CTLs) to eradicate the tumor. DCs represent a heterogeneous cell population, including conventional DCs (cDCs), consisting of cDC1s, cDC2s, plasmacyto...

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Bibliographic Details
Main Authors: Anne Huber, Floris Dammeijer, Joachim G. J. V. Aerts, Heleen Vroman
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Immunology
Subjects:
dendritic cell (DC)
Immunotherapy
DC subsets
T cell responses
tumor immunology
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02804/full

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