A young child with HIV and unsteady gait: A case report

A young child with HIV and unsteady gait: A case report

Background: We would like to raise awareness about the toxicities related to the added excipients present in the oral solution of Liponavir/ritonavir in particular alcohol and propylene glycol. Case presentation: In this case report, we describe an 18 month-old child with a newly diagnosed HIV infec...

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Main Authors: Nadine Yazbeck, Yolla Youssef, Rima Hanna-Wakim
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:IDCases
Online Access:http://www.sciencedirect.com/science/article/pii/S2214250919302823
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spelling doaj-c2d1320faac244c68bb83a20adf324d02021-07-02T12:23:45ZengElsevierIDCases2214-25092020-01-0119A young child with HIV and unsteady gait: A case reportNadine Yazbeck0Yolla Youssef1Rima Hanna-Wakim2Department of Pediatrics and Adolescent Medicine, American University of Beirut Medical Center, Beirut, LebanonDepartment of Pediatrics and Adolescent Medicine, American University of Beirut Medical Center, Beirut, Lebanon; Division of Pediatric Infectious Diseases, Department of Pediatrics and Adolescent Medicine, Lebanon; Center for Infectious Diseases Research, American University of Beirut Medical Center, Beirut, LebanonDepartment of Pediatrics and Adolescent Medicine, American University of Beirut Medical Center, Beirut, Lebanon; Division of Pediatric Infectious Diseases, Department of Pediatrics and Adolescent Medicine, Lebanon; Center for Infectious Diseases Research, American University of Beirut Medical Center, Beirut, Lebanon; Corresponding author at: American University of Beirut, Riad El Solh 110 72020, Beirut, Lebanon.Background: We would like to raise awareness about the toxicities related to the added excipients present in the oral solution of Liponavir/ritonavir in particular alcohol and propylene glycol. Case presentation: In this case report, we describe an 18 month-old child with a newly diagnosed HIV infection on antiretroviral therapy (ART). She developed shortly after starting the ART unsteady gait and imbalance. Conclusions: The excipient-excipient interaction in Lopinavir/ritonavir may contribute to major toxicities not only in premature neonates and infants; but also in older children specifically from Asian ethnicity. Keywords: HIV, Lopinavir-ritonavir, Unsteady gaithttp://www.sciencedirect.com/science/article/pii/S2214250919302823
collection DOAJ
language English
format Article
sources DOAJ
author Nadine Yazbeck
Yolla Youssef
Rima Hanna-Wakim
spellingShingle Nadine Yazbeck
Yolla Youssef
Rima Hanna-Wakim
A young child with HIV and unsteady gait: A case report
IDCases
author_facet Nadine Yazbeck
Yolla Youssef
Rima Hanna-Wakim
author_sort Nadine Yazbeck
title A young child with HIV and unsteady gait: A case report
title_short A young child with HIV and unsteady gait: A case report
title_full A young child with HIV and unsteady gait: A case report
title_fullStr A young child with HIV and unsteady gait: A case report
title_full_unstemmed A young child with HIV and unsteady gait: A case report
title_sort young child with hiv and unsteady gait: a case report
publisher Elsevier
series IDCases
issn 2214-2509
publishDate 2020-01-01
description Background: We would like to raise awareness about the toxicities related to the added excipients present in the oral solution of Liponavir/ritonavir in particular alcohol and propylene glycol. Case presentation: In this case report, we describe an 18 month-old child with a newly diagnosed HIV infection on antiretroviral therapy (ART). She developed shortly after starting the ART unsteady gait and imbalance. Conclusions: The excipient-excipient interaction in Lopinavir/ritonavir may contribute to major toxicities not only in premature neonates and infants; but also in older children specifically from Asian ethnicity. Keywords: HIV, Lopinavir-ritonavir, Unsteady gait
url http://www.sciencedirect.com/science/article/pii/S2214250919302823
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AT yollayoussef ayoungchildwithhivandunsteadygaitacasereport
AT rimahannawakim ayoungchildwithhivandunsteadygaitacasereport
AT nadineyazbeck youngchildwithhivandunsteadygaitacasereport
AT yollayoussef youngchildwithhivandunsteadygaitacasereport
AT rimahannawakim youngchildwithhivandunsteadygaitacasereport
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