Upregulation of MUC5AC by VEGF in human primary bronchial epithelial cells: implications for asthma

Upregulation of MUC5AC by VEGF in human primary bronchial epithelial cells: implications for asthma

Abstract Background Airway mucus hypersecretion is an important pathophysiological feature in asthma. Mucins are glycoproteins that are mainly responsible for the viscoelastic property of mucus, and MUC5AC is a major mucin glycoprotein that is overproduced in asthma. Vascular endothelial growth fact...

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Bibliographic Details
Main Authors: Sung-Ho Kim, Qing-Mei Pei, Ping Jiang, Juan Liu, Rong-Fei Sun, Xue-Jiao Qian, Jiang-Bo Liu
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Respiratory Research
Subjects:
Asthma
Vascular endothelial growth factor
MUC5AC
Caveolin-1
Online Access:https://doi.org/10.1186/s12931-019-1245-1

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