Computational identification of mutually homologous Zika virus miRNAs that target microcephaly genes

Computational identification of mutually homologous Zika virus miRNAs that target microcephaly genes

Background Zika virus (ZIKV) has been associated with a variety of neuropathologies, including microcephaly. We hypothesize that ZIKV genes activate host microRNAs (miRNAs) causing dysfunctional development of human fetal brains. Objectives/methods A bioinformatics search for miRNA genome-wide bindi...

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Bibliographic Details
Main Authors: Ewen McLean, Roshan Bhattarai, Brandon W. Hughes, Kuhanandha Mahalingam, Omar Bagasra
Format: Article
Language:English
Published: Taylor & Francis Group 2017-01-01
Series:Libyan Journal of Medicine
Subjects:
Zika virus
microcephaly
miRNAs
Online Access:http://dx.doi.org/10.1080/19932820.2017.1304505

Internet

http://dx.doi.org/10.1080/19932820.2017.1304505

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