Multi-Modal Mass Spectrometric Imaging of Uveal Melanoma

Multi-Modal Mass Spectrometric Imaging of Uveal Melanoma

Matrix assisted laser desorption ionisation mass spectrometry imaging (MALDI-MSI), was used to obtain images of lipids and metabolite distribution in formalin fixed and embedded in paraffin (FFPE) whole eye sections containing primary uveal melanomas (UM). Using this technique, it was possible to ob...

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Bibliographic Details
Main Authors: Laura M. Cole, Joshua Handley, Emmanuelle Claude, Catherine J. Duckett, Hardeep S. Mudhar, Karen Sisley, Malcolm R. Clench
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Metabolites
Subjects:
uveal melanoma mass spectrometry imaging
matrix assisted laser desorption ionisation
laser ablation inductively coupled plasma
cancer progression
genetic biomarkers
heterogeneity
Online Access:https://www.mdpi.com/2218-1989/11/8/560

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