Modeling the interaction between quinolinate and the receptor for advanced glycation end products (RAGE): relevance for early neuropathological processes.

The receptor for advanced glycation end products (RAGE) is a pattern-recognition receptor involved in neurodegenerative and inflammatory disorders. RAGE induces cellular signaling upon binding to a variety of ligands. Evidence suggests that RAGE up-regulation is involved in quinolinate (QUIN)-induce...

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Bibliographic Details
Main Authors: Iris N Serratos, Pilar Castellanos, Nina Pastor, César Millán-Pacheco, Daniel Rembao, Ruy Pérez-Montfort, Nallely Cabrera, Francisco Reyes-Espinosa, Paulina Díaz-Garrido, Ambar López-Macay, Karina Martínez-Flores, Alberto López-Reyes, Aurora Sánchez-García, Elvis Cuevas, Abel Santamaria
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4354912?pdf=render