In vitro and in vivo characterization of domperidone-loaded fast dissolving buccal films

The delivery of drugs via fast dissolving films is an effective alternative for drugs with low bioavailability when administered by other routes. This is the case of domperidone (DMP) an anti-emetic drug with low water solubility and vulnerable to extensive first-pass effect. To overcome these limit...

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Bibliographic Details
Main Authors: Gamal M. Zayed, Saleh Abd-El Rasoul, Mohamed A. Ibrahim, Mohammed S. Saddik, Doaa H. Alshora
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Saudi Pharmaceutical Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016420300062