A Diverse Stochastic Search Algorithm for Combination Therapeutics

Background. Design of drug combination cocktails to maximize sensitivity for individual patients presents a challenge in terms of minimizing the number of experiments to attain the desired objective. The enormous number of possible drug combinations constrains exhaustive experimentation approaches,...

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Bibliographic Details
Main Authors: Mehmet Umut Caglar, Ranadip Pal
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2014/873436