Optofluidic Lab-on-a-Chip Fluorescence Sensor Using Integrated Buried ARROW (bARROW) Waveguides

Optofluidic, lab-on-a-chip fluorescence sensors were fabricated using buried anti-resonant reflecting optical waveguides (bARROWs). The bARROWs are impervious to the negative water absorption effects that typically occur in waveguides made using hygroscopic, plasma-enhanced chemical vapor deposition...

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Main Authors: Thomas Wall, Johnny McMurray, Gopikrishnan Meena, Vahid Ganjalizadeh, Holger Schmidt, Aaron R. Hawkins
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:Micromachines
Subjects:
Online Access:https://www.mdpi.com/2072-666X/8/8/252
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spelling doaj-c29ede00a8344411b31458bdb2303e7f2020-11-25T00:53:32ZengMDPI AGMicromachines2072-666X2017-08-018825210.3390/mi8080252mi8080252Optofluidic Lab-on-a-Chip Fluorescence Sensor Using Integrated Buried ARROW (bARROW) WaveguidesThomas Wall0Johnny McMurray1Gopikrishnan Meena2Vahid Ganjalizadeh3Holger Schmidt4Aaron R. Hawkins5Electrical and Computer Engineering, Brigham Young University, Provo, UT 84602, USAElectrical and Computer Engineering, Brigham Young University, Provo, UT 84602, USABaskin School of Engineering, University of California, Santa Cruz, Santa Cruz, CA 95064, USABaskin School of Engineering, University of California, Santa Cruz, Santa Cruz, CA 95064, USABaskin School of Engineering, University of California, Santa Cruz, Santa Cruz, CA 95064, USAElectrical and Computer Engineering, Brigham Young University, Provo, UT 84602, USAOptofluidic, lab-on-a-chip fluorescence sensors were fabricated using buried anti-resonant reflecting optical waveguides (bARROWs). The bARROWs are impervious to the negative water absorption effects that typically occur in waveguides made using hygroscopic, plasma-enhanced chemical vapor deposition (PECVD) oxides. These sensors were used to detect fluorescent microbeads and had an average signal-to-noise ratio (SNR) that was 81.3% higher than that of single-oxide ARROW fluorescence sensors. While the single-oxide ARROW sensors were annealed at 300 °C to drive moisture out of the waveguides, the bARROW sensors required no annealing process to obtain a high SNR.https://www.mdpi.com/2072-666X/8/8/252optofluidicslab-on-a-chipfluorescence sensingPECVDSiO2water absorption
collection DOAJ
language English
format Article
sources DOAJ
author Thomas Wall
Johnny McMurray
Gopikrishnan Meena
Vahid Ganjalizadeh
Holger Schmidt
Aaron R. Hawkins
spellingShingle Thomas Wall
Johnny McMurray
Gopikrishnan Meena
Vahid Ganjalizadeh
Holger Schmidt
Aaron R. Hawkins
Optofluidic Lab-on-a-Chip Fluorescence Sensor Using Integrated Buried ARROW (bARROW) Waveguides
Micromachines
optofluidics
lab-on-a-chip
fluorescence sensing
PECVD
SiO2
water absorption
author_facet Thomas Wall
Johnny McMurray
Gopikrishnan Meena
Vahid Ganjalizadeh
Holger Schmidt
Aaron R. Hawkins
author_sort Thomas Wall
title Optofluidic Lab-on-a-Chip Fluorescence Sensor Using Integrated Buried ARROW (bARROW) Waveguides
title_short Optofluidic Lab-on-a-Chip Fluorescence Sensor Using Integrated Buried ARROW (bARROW) Waveguides
title_full Optofluidic Lab-on-a-Chip Fluorescence Sensor Using Integrated Buried ARROW (bARROW) Waveguides
title_fullStr Optofluidic Lab-on-a-Chip Fluorescence Sensor Using Integrated Buried ARROW (bARROW) Waveguides
title_full_unstemmed Optofluidic Lab-on-a-Chip Fluorescence Sensor Using Integrated Buried ARROW (bARROW) Waveguides
title_sort optofluidic lab-on-a-chip fluorescence sensor using integrated buried arrow (barrow) waveguides
publisher MDPI AG
series Micromachines
issn 2072-666X
publishDate 2017-08-01
description Optofluidic, lab-on-a-chip fluorescence sensors were fabricated using buried anti-resonant reflecting optical waveguides (bARROWs). The bARROWs are impervious to the negative water absorption effects that typically occur in waveguides made using hygroscopic, plasma-enhanced chemical vapor deposition (PECVD) oxides. These sensors were used to detect fluorescent microbeads and had an average signal-to-noise ratio (SNR) that was 81.3% higher than that of single-oxide ARROW fluorescence sensors. While the single-oxide ARROW sensors were annealed at 300 °C to drive moisture out of the waveguides, the bARROW sensors required no annealing process to obtain a high SNR.
topic optofluidics
lab-on-a-chip
fluorescence sensing
PECVD
SiO2
water absorption
url https://www.mdpi.com/2072-666X/8/8/252
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