Large-scale, cross-flow based isolation of highly pure and endocytosis-competent extracellular vesicles

Large-scale, cross-flow based isolation of highly pure and endocytosis-competent extracellular vesicles

Isolation of extracellular vesicles (EVs) from cell culture supernatant or plasma can be accomplished in a variety of ways. Common measures to quantify relative success are: concentration of the EVs, purity from non-EVs associated protein, size homogeneity and functionality of the final product. Her...

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Bibliographic Details
Main Authors: Ryan P. McNamara, Carolina P. Caro-Vegas, Lindsey M. Costantini, Justin T. Landis, Jack D. Griffith, Blossom A. Damania, Dirk P. Dittmer
Format: Article
Language:English
Published: Taylor & Francis Group 2018-12-01
Series:Journal of Extracellular Vesicles
Subjects:
Extracellular vesicles
industrial scale
tangential flow
cross-flow
capto core
Online Access:http://dx.doi.org/10.1080/20013078.2018.1541396

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