Impact of Electrical Pulse Pattern on Red Blood Cell Membranous Electroporation

Impact of Electrical Pulse Pattern on Red Blood Cell Membranous Electroporation

The impact of the pattern of a pulse electrical field generated by a defibrillator discharge on the efficiency of membranous electroporation was studied in a model experiment on human erythrocytic suspension. The initial temperature and time parameters of the model were substantiated. The rate of ce...

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Main Authors: Ye. K. Kozlova, V. V. Moroz, M. S. Bogushevich, P. Yu. Alekseyeva, A. M. Chernysh
Format: Article
Language:Russian
Published: Russian Academy of Medical Sciences 2005-02-01
Series:Obŝaâ Reanimatologiâ
Online Access:https://www.reanimatology.com/rmt/article/view/1321
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spelling doaj-c29c6ace936a44f1993375ee10a76a2c2021-07-28T21:21:45ZrusRussian Academy of Medical SciencesObŝaâ Reanimatologiâ1813-97792411-71102005-02-0111424610.15360/1813-9779-2005-1-42-461321Impact of Electrical Pulse Pattern on Red Blood Cell Membranous ElectroporationYe. K. Kozlova0V. V. Moroz1M. S. Bogushevich2P. Yu. Alekseyeva3A. M. Chernysh4Research Institute of General Reanimatology, Russian Academy of Medical Sciences, Moscow I. M. Sechenov Moscow Medical AcademyResearch Institute of General Reanimatology, Russian Academy of Medical Sciences, Moscow I. M. Sechenov Moscow Medical AcademyResearch Institute of General Reanimatology, Russian Academy of Medical Sciences, Moscow I. M. Sechenov Moscow Medical AcademyResearch Institute of General Reanimatology, Russian Academy of Medical Sciences, Moscow I. M. Sechenov Moscow Medical AcademyResearch Institute of General Reanimatology, Russian Academy of Medical Sciences, Moscow I. M. Sechenov Moscow Medical AcademyThe impact of the pattern of a pulse electrical field generated by a defibrillator discharge on the efficiency of membranous electroporation was studied in a model experiment on human erythrocytic suspension. The initial temperature and time parameters of the model were substantiated. The rate of cellular hemolysis under the action of two impulses was shown to be increased by 1.2—3.5 times as compared with that under the action of one impulse. Electroporation was more effective and its threshold was lower under the action of two heterodirectional pulses as compared with that under the action of two unidirectional ones. These dependencies are statistical.https://www.reanimatology.com/rmt/article/view/1321
collection DOAJ
language Russian
format Article
sources DOAJ
author Ye. K. Kozlova
V. V. Moroz
M. S. Bogushevich
P. Yu. Alekseyeva
A. M. Chernysh
spellingShingle Ye. K. Kozlova
V. V. Moroz
M. S. Bogushevich
P. Yu. Alekseyeva
A. M. Chernysh
Impact of Electrical Pulse Pattern on Red Blood Cell Membranous Electroporation
Obŝaâ Reanimatologiâ
author_facet Ye. K. Kozlova
V. V. Moroz
M. S. Bogushevich
P. Yu. Alekseyeva
A. M. Chernysh
author_sort Ye. K. Kozlova
title Impact of Electrical Pulse Pattern on Red Blood Cell Membranous Electroporation
title_short Impact of Electrical Pulse Pattern on Red Blood Cell Membranous Electroporation
title_full Impact of Electrical Pulse Pattern on Red Blood Cell Membranous Electroporation
title_fullStr Impact of Electrical Pulse Pattern on Red Blood Cell Membranous Electroporation
title_full_unstemmed Impact of Electrical Pulse Pattern on Red Blood Cell Membranous Electroporation
title_sort impact of electrical pulse pattern on red blood cell membranous electroporation
publisher Russian Academy of Medical Sciences
series Obŝaâ Reanimatologiâ
issn 1813-9779
2411-7110
publishDate 2005-02-01
description The impact of the pattern of a pulse electrical field generated by a defibrillator discharge on the efficiency of membranous electroporation was studied in a model experiment on human erythrocytic suspension. The initial temperature and time parameters of the model were substantiated. The rate of cellular hemolysis under the action of two impulses was shown to be increased by 1.2—3.5 times as compared with that under the action of one impulse. Electroporation was more effective and its threshold was lower under the action of two heterodirectional pulses as compared with that under the action of two unidirectional ones. These dependencies are statistical.
url https://www.reanimatology.com/rmt/article/view/1321
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AT msbogushevich impactofelectricalpulsepatternonredbloodcellmembranouselectroporation
AT pyualekseyeva impactofelectricalpulsepatternonredbloodcellmembranouselectroporation
AT amchernysh impactofelectricalpulsepatternonredbloodcellmembranouselectroporation
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