An Alternative HIV-1 Non-Nucleoside Reverse Transcriptase Inhibition Mechanism: Targeting the p51 Subunit

An Alternative HIV-1 Non-Nucleoside Reverse Transcriptase Inhibition Mechanism: Targeting the p51 Subunit

The ongoing development of drug resistance in HIV continues to push for the need of alternative drug targets in inhibiting HIV. One such target is the Reverse transcriptase (RT) enzyme which is unique and critical in the viral life cycle—a rational target that is likely to have less off-target effec...

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Bibliographic Details
Main Authors: Kwok-Fong Chan, Chinh Tran-To Su, Alexander Krah, Ser-Xian Phua, Joshua Yi Yeo, Wei-Li Ling, Peter J. Bond, Samuel Ken-En Gan
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Molecules
Subjects:
HIV
novel p51 drug target
NNRTIs
drug resistance
Online Access:https://www.mdpi.com/1420-3049/25/24/5902

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