Benzyl isothiocyanate (BITC) triggers mitochondria-mediated apoptotic machinery in human cisplatin-resistant oral cancer CAR cells

Benzyl isothiocyanate (BITC) triggers mitochondria-mediated apoptotic machinery in human cisplatin-resistant oral cancer CAR cells

Benzyl isothiocyanate (BITC), a component of dietary food, possesses a powerful anticancer activity. Previous studies have shown that BITC produces a large number of intracellular reactive oxygen species (ROS) and increases intracellular Ca2+ release from endoplasmic reticulum (ER), leading to the a...

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Bibliographic Details
Main Authors: Lee Chiu-Fang, Chiang Ni-Na, Lu Yao-Hua, Huang Yu-Syuan, Yang Jai-Sing, Tsai Shih-Chang, Lu Chi-Cheng, Chen Fu-An
Format: Article
Language:English
Published: China Medical University 2018-09-01
Series:BioMedicine
Subjects:
Benzyl isothiocyanate (BITC)
Human cisplatin-resistant oral cancer CAR cells
Apoptosis
Mitochondria
Online Access:https://doi.org/10.1051/bmdcn/2018080315

Internet

https://doi.org/10.1051/bmdcn/2018080315

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