Prospective breast cancer risk factors prediction in Saudi women

• Main Authors: Sawsan Babiker, Omaima Nasir, S.H. Alotaibi, Alaa Marzogi, Mohammad Bogari, Tahani Alghamdi
• Format: Article
• Language: English
• Published: Elsevier 2020-06-01
• Series: Saudi Journal of Biological Sciences
• Subjects: Breast cancer; Risk Factors; Logistic Regression; Saudi women
• Online Access: http://www.sciencedirect.com/science/article/pii/S1319562X20300656

Women's health is affected by breast cancer worldwide and Saudi Arabia (SA) is no exception. Malignancy has enormous consequences for social, psychological and public health. The aim of this study was to examine the risk factors for Saudi women from breast cancer using logistic regression models. In 135 patient cases for different stages of breast cancer was used to study case management, 270 healthy women from King Abd Alla Medical City, Mecca, SA were taken to predict the probability of women developing breast cancer, logistic regression was analyzed taking factors such as age, marital status, family history, parity, age at first full-term pregnancy, menopausal status, body mass index (BMI) and breast feeding. The logistic regression model showed that there are important risk factors (age, marital status, family history, parity, age at first full-term pregnancy, menopausal status, body mass index, and breast feeding) in development of breast cancer. Fewer cases were observed in unmarried women, age ≤30, BMI ≤20. In contrast, more cases were found with women age 41–50 married, BMI > 30, a smaller number of children, not breast feeding, age of first pregnancy ≥30, menopausal status age at 46–50. Based on our data there is role of risk factors in developing breast cancer, less BMI, the increase number of children, breast feeding, which are playing as protective factor for breast cancer.