Clinical Experience of Proteasome Inhibitor Bortezomib Regarding Efficacy and Safety in Severe Systemic Lupus Erythematosus: A Nationwide Study

Clinical Experience of Proteasome Inhibitor Bortezomib Regarding Efficacy and Safety in Severe Systemic Lupus Erythematosus: A Nationwide Study

As treatment options in advanced systematic lupus erythematosus (SLE) are limited, there is an urgent need for new and effective therapeutic alternatives for selected cases with severe disease. Bortezomib (BTZ) is a specific, reversible, inhibitor of the 20S subunit of the proteasome. Herein, we rep...

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Bibliographic Details
Main Authors:	Tomas Walhelm, Iva Gunnarsson, Rebecca Heijke, Dag Leonard, Estelle Trysberg, Per Eriksson, Christopher Sjöwall
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-10-01
Series:	Frontiers in Immunology
Subjects:	bortezomib (BTZ) systemic lupus - erythematosus Lupus nephritis (LN) adverse (side) effects antinuclear antibodies clinical efficacy analysis
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.756941/full

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