Extracellular Vesicles Derived Human-miRNAs Modulate the Immune System in Type 1 Diabetes

Extracellular Vesicles Derived Human-miRNAs Modulate the Immune System in Type 1 Diabetes

Extracellular vesicles with their molecular cargo can modulate target cell response and may affect the pathogenesis of diseases. The extracellular vesicles containing micro-RNAs (miRNAs), which are often studied as disease biomarkers, but rarely as mediators of the disease development. The role of e...

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Bibliographic Details
Main Authors: Tine Tesovnik, Jernej Kovač, Katka Pohar, Samo Hudoklin, Klemen Dovč, Nataša Bratina, Katarina Trebušak Podkrajšek, Maruša Debeljak, Peter Veranič, Emanuele Bosi, Lorenzo Piemonti, Alojz Ihan, Tadej Battelino
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
type 1 diabetes
extracellular vesicles
miRNA
immune modulating activity
autoimmune disease
TLR7/8
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00202/full

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