Age-Related Macular Degeneration: Advances in Management and Diagnosis

Age-related macular degeneration (AMD) is the most common cause of irreversible visual impairment in older populations in industrialized nations. AMD is a late-onset deterioration of photoreceptors and retinal pigment epithelium in the central retina caused by various environmental and genetic fact...

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Main Authors: Yoshihiro Yonekawa, Joan W. Miller, Ivana K. Kim
Format: Article
Language:English
Published: MDPI AG 2015-02-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:http://www.mdpi.com/2077-0383/4/2/343
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spelling doaj-c2754ebbf4c84f07b7b04106714183e82020-11-24T22:35:07ZengMDPI AGJournal of Clinical Medicine2077-03832015-02-014234335910.3390/jcm4020343jcm4020343Age-Related Macular Degeneration: Advances in Management and DiagnosisYoshihiro Yonekawa0Joan W. Miller1Ivana K. Kim2Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USARetina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USARetina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USAAge-related macular degeneration (AMD) is the most common cause of irreversible visual impairment in older populations in industrialized nations. AMD is a late-onset deterioration of photoreceptors and retinal pigment epithelium in the central retina caused by various environmental and genetic factors. Great strides in our understanding of AMD pathogenesis have been made in the past several decades, which have translated into revolutionary therapeutic agents in recent years. In this review, we describe the clinical and pathologic features of AMD and present an overview of current diagnosis and treatment strategies.http://www.mdpi.com/2077-0383/4/2/343age-related macular degenerationchoroidal neovascularizationfundus autofluorescencefluorescein angiographyoptical coherence tomographyretinavascular endothelial growth factorvisual impairment
collection DOAJ
language English
format Article
sources DOAJ
author Yoshihiro Yonekawa
Joan W. Miller
Ivana K. Kim
spellingShingle Yoshihiro Yonekawa
Joan W. Miller
Ivana K. Kim
Age-Related Macular Degeneration: Advances in Management and Diagnosis
Journal of Clinical Medicine
age-related macular degeneration
choroidal neovascularization
fundus autofluorescence
fluorescein angiography
optical coherence tomography
retina
vascular endothelial growth factor
visual impairment
author_facet Yoshihiro Yonekawa
Joan W. Miller
Ivana K. Kim
author_sort Yoshihiro Yonekawa
title Age-Related Macular Degeneration: Advances in Management and Diagnosis
title_short Age-Related Macular Degeneration: Advances in Management and Diagnosis
title_full Age-Related Macular Degeneration: Advances in Management and Diagnosis
title_fullStr Age-Related Macular Degeneration: Advances in Management and Diagnosis
title_full_unstemmed Age-Related Macular Degeneration: Advances in Management and Diagnosis
title_sort age-related macular degeneration: advances in management and diagnosis
publisher MDPI AG
series Journal of Clinical Medicine
issn 2077-0383
publishDate 2015-02-01
description Age-related macular degeneration (AMD) is the most common cause of irreversible visual impairment in older populations in industrialized nations. AMD is a late-onset deterioration of photoreceptors and retinal pigment epithelium in the central retina caused by various environmental and genetic factors. Great strides in our understanding of AMD pathogenesis have been made in the past several decades, which have translated into revolutionary therapeutic agents in recent years. In this review, we describe the clinical and pathologic features of AMD and present an overview of current diagnosis and treatment strategies.
topic age-related macular degeneration
choroidal neovascularization
fundus autofluorescence
fluorescein angiography
optical coherence tomography
retina
vascular endothelial growth factor
visual impairment
url http://www.mdpi.com/2077-0383/4/2/343
work_keys_str_mv AT yoshihiroyonekawa agerelatedmaculardegenerationadvancesinmanagementanddiagnosis
AT joanwmiller agerelatedmaculardegenerationadvancesinmanagementanddiagnosis
AT ivanakkim agerelatedmaculardegenerationadvancesinmanagementanddiagnosis
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