Application of convolutional neural networks towards nuclei segmentation in localization-based super-resolution fluorescence microscopy images

Abstract Background Automated segmentation of nuclei in microscopic images has been conducted to enhance throughput in pathological diagnostics and biological research. Segmentation accuracy and speed has been significantly enhanced with the advent of convolutional neural networks. A barrier in the...

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Bibliographic Details
Main Authors: Christopher A. Mela, Yang Liu
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-021-04245-x