BabA-mediated adherence of pediatric ulcerogenic H. pylori strains to gastric mucins at neutral and acidic pH

Helicobacter pylori infection can result in non-ulcer dyspepsia (NUD), peptic ulcer disease (PUD), adenocarcinoma, and gastric lymphoma. H. pylori reside within the gastric mucus layer, mainly composed of mucins carrying an array of glycan structures that can serve as bacterial adhesion epitopes. Th...

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Bibliographic Details
Main Authors: Macarena P. Quintana-Hayashi, Raquel Rocha, Médea Padra, Anders Thorell, Chunsheng Jin, Niclas G. Karlsson, Mónica Roxo-Rosa, Mónica Oleastro, Sara K. Lindén
Format: Article
Language:English
Published: Taylor & Francis Group 2018-12-01
Series:Virulence
Subjects:
pH
Online Access:http://dx.doi.org/10.1080/21505594.2018.1532243