Looking Back, Looking Forward at Halogen Bonding in Drug Discovery

Looking Back, Looking Forward at Halogen Bonding in Drug Discovery

Halogen bonding has emerged at the forefront of advances in improving ligand: receptor interactions. In particular the newfound ability of this extant non-covalent-bonding phenomena has revolutionized computational approaches to drug discovery while simultaneously reenergizing synthetic approaches t...

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Bibliographic Details
Main Authors: Lois Mendez, Gabriela Henriquez, Suman Sirimulla, Mahesh Narayan
Format: Article
Language:English
Published: MDPI AG 2017-08-01
Series:Molecules
Subjects:
halogen bonding
sigma-hole
Lewis base
Lewis acid
drug discovery
Online Access:https://www.mdpi.com/1420-3049/22/9/1397

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