Adhesion G protein-coupled receptor, ELTD1, is a potential therapeutic target for retinoblastoma migration and invasion

Adhesion G protein-coupled receptor, ELTD1, is a potential therapeutic target for retinoblastoma migration and invasion

Abstract Background Prognosis for pediatric metastatic Retinoblastoma (Rb) is poor and current therapies are limited by high systemic toxicity rates and insufficient therapeutic efficacy for metastatic Rb. Tumor dissemination to the brain is promoted by the heterogeneous adhesive and invasive proper...

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Bibliographic Details
Main Authors: Jonathan Guihurt Santiago, Neikelyn Burgos-Tirado, Daniella Dorta Lafontaine, José C. Mendoza Sierra, Roberto Herrera Camacho, Clara M. Vecchini Rodríguez, Vanessa Morales-Tirado, Jacqueline Flores-Otero
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Cancer
Subjects:
Retinoblastoma
Adhesion-GPCRs
ELTD1
GPR125
Intraocular cancer
Online Access:https://doi.org/10.1186/s12885-020-07768-3

Internet

https://doi.org/10.1186/s12885-020-07768-3

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