Bovine ephemeral fever virus triggers autophagy enhancing virus replication via upregulation of the Src/JNK/AP1 and PI3K/Akt/NF-κB pathways and suppression of the PI3K/Akt/mTOR pathway

Bovine ephemeral fever virus triggers autophagy enhancing virus replication via upregulation of the Src/JNK/AP1 and PI3K/Akt/NF-κB pathways and suppression of the PI3K/Akt/mTOR pathway

Abstract Autophagy plays an important role in cellular response to pathogens. However, the impact of the autophagy machinery on bovine ephemeral fever virus (BEFV) infection is not yet determined. A recent study in our laboratory demonstrated that BEFV triggers simultaneously the PI3K/Akt/NF-κB and...

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Bibliographic Details
Main Authors: Ching-Yuan Cheng, Hsu-Hung Tseng, Hung-Chuan Chiu, Ching-Dong Chang, Brent L. Nielsen, Hung-Jen Liu
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Veterinary Research
Online Access:http://link.springer.com/article/10.1186/s13567-019-0697-0

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