RNA variant identification discrepancy among splice-aware alignment algorithms.

Next-generation sequencing (NGS) techniques have been generating various molecular maps, including transcriptomes via RNA-seq. Although the primary purpose of RNA-seq is to quantify the expression level of known genes, RNA variants are also identifiable. However, care must be taken to account for RN...

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Bibliographic Details
Main Authors: Ji Hyung Hong, Yoon Ho Ko, Keunsoo Kang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6072070?pdf=render

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