Avaliação da Reprodutibilidade das Medições da Espessura da Camada de Fibras Nervosas Peripapilar usando o OCT de Domínio Espectral

• Main Authors: Ines Coutinho, Mafalda Mota, Catarina Pedrosa, Mário Ramalho, Cristina Santos, Fernando Vaz
• Format: Article
• Language: English
• Published: Pan-American Association of Ophthalmology 2015-05-01
• Series: Vision Pan-America
• Subjects: optical coherence tomography; glaucomatous neuropathy; peripapilary retinal nerve fiber layer
• Online Access: http://journals.sfu.ca/paao/index.php/journal/article/view/254
• ISSN: 2219-4665; 2219-4673

Purpose: To assess the reproducibility of peripapillary retinal nerve fiber layer (RNFL) thickness, measured with Spectralis® OCT, in healthy and glaucomatous subjects, through of inter-examiner variability, intra-test and inter-test with and without software of followup. Methods: Cross-sectional and prospective study with 37 controls (63 eyes) and 33 patients with glaucomatous optic neuropathy (55 eyes). Intraclass correlation coefficient (ICC) and coefficient of variation (CV) were calculated. Results: Low inter-examiner, intra-test and inter-test variability, with ICC>0,75 e CV<10%, in both control group and patients with glaucoma. Conclusions: The Spectralis® OCT shows excellent reproducibility of RNFL measurements, validating it as an useful tool for monitoring the progression of glaucoma.