A facile fabrication of novel stuff with antibacterial property and osteogenic promotion utilizing red phosphorus and near-infrared light

A facile fabrication of novel stuff with antibacterial property and osteogenic promotion utilizing red phosphorus and near-infrared light

Bone-implant materials are important for bone repairing and orthopedics surgery, which include bone plates and bone nails. These materials need to be designed not only considering its biostability and biocompatibility, but also their by-products induced infection after therapy or long-time treatment...

Full description

Bibliographic Details
Main Authors: Bo Huang, Lei Tan, Xiangmei Liu, Jun Li, Shuilin Wu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2019-12-01
Series:Bioactive Materials
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X1830063X
id doaj-c20946f39c4949018c08df253abe1d65
record_format Article
spelling doaj-c20946f39c4949018c08df253abe1d652021-02-02T05:11:29ZengKeAi Communications Co., Ltd.Bioactive Materials2452-199X2019-12-0141721A facile fabrication of novel stuff with antibacterial property and osteogenic promotion utilizing red phosphorus and near-infrared lightBo Huang0Lei Tan1Xiangmei Liu2Jun Li3Shuilin Wu4Ministry-of-Education Key Laboratory for the Green Preparation and Application of Functional Materials, Hubei Key Laboratory of Polymer Materials, School of Materials Science & Engineering, Hubei University, Wuhan, 430062, ChinaMinistry-of-Education Key Laboratory for the Green Preparation and Application of Functional Materials, Hubei Key Laboratory of Polymer Materials, School of Materials Science & Engineering, Hubei University, Wuhan, 430062, ChinaMinistry-of-Education Key Laboratory for the Green Preparation and Application of Functional Materials, Hubei Key Laboratory of Polymer Materials, School of Materials Science & Engineering, Hubei University, Wuhan, 430062, China; Corresponding author.School of Materials Science & Engineering, The Key Laboratory of Advanced Ceramics and Machining Technology by the Ministry of Education of China, Tianjin University, Tianjin, 300072, ChinaMinistry-of-Education Key Laboratory for the Green Preparation and Application of Functional Materials, Hubei Key Laboratory of Polymer Materials, School of Materials Science & Engineering, Hubei University, Wuhan, 430062, China; School of Materials Science & Engineering, The Key Laboratory of Advanced Ceramics and Machining Technology by the Ministry of Education of China, Tianjin University, Tianjin, 300072, China; Corresponding author. Ministry-of-Education Key Laboratory for the Green Preparation and Application of Functional Materials, Hubei Key Laboratory of Polymer Materials, School of Materials Science & Engineering, Hubei University, Wuhan, 430062, China.Bone-implant materials are important for bone repairing and orthopedics surgery, which include bone plates and bone nails. These materials need to be designed not only considering its biostability and biocompatibility, but also their by-products induced infection after therapy or long-time treatment in vivo. Thus, the development of novel implant materials is quite urgent. Red phosphorus has great biocompatibility and exhibits efficient photothermal ability. Herein, a red phosphorus/IR780/arginine-glycine-asparticacid-cysteine (RGDC) coating on titanium bone-implant was prepared. The temperature sensitivity of Staphylococcus aureus biofilm is enhanced in the presence of ROS produced by IR780 with 808 nm light irradiation. With keeping the cells and tissues normal, a high antibacterial performance can be realized by near-infrared (808 nm) irradiated within 10 min at 50 °C. Besides the high effective antibacterial efficacy provided by photothermal therapy (PTT) and photodynamic therapy (PDT), the RGDC decorated surface can also possess an excellent performance in osteogenesis in vivo. Keywords: Implants, Red phosphorus, Near-infrared, Osteogenesis, Antibacterial, Biofilmhttp://www.sciencedirect.com/science/article/pii/S2452199X1830063X
collection DOAJ
language English
format Article
sources DOAJ
author Bo Huang
Lei Tan
Xiangmei Liu
Jun Li
Shuilin Wu
spellingShingle Bo Huang
Lei Tan
Xiangmei Liu
Jun Li
Shuilin Wu
A facile fabrication of novel stuff with antibacterial property and osteogenic promotion utilizing red phosphorus and near-infrared light
Bioactive Materials
author_facet Bo Huang
Lei Tan
Xiangmei Liu
Jun Li
Shuilin Wu
author_sort Bo Huang
title A facile fabrication of novel stuff with antibacterial property and osteogenic promotion utilizing red phosphorus and near-infrared light
title_short A facile fabrication of novel stuff with antibacterial property and osteogenic promotion utilizing red phosphorus and near-infrared light
title_full A facile fabrication of novel stuff with antibacterial property and osteogenic promotion utilizing red phosphorus and near-infrared light
title_fullStr A facile fabrication of novel stuff with antibacterial property and osteogenic promotion utilizing red phosphorus and near-infrared light
title_full_unstemmed A facile fabrication of novel stuff with antibacterial property and osteogenic promotion utilizing red phosphorus and near-infrared light
title_sort facile fabrication of novel stuff with antibacterial property and osteogenic promotion utilizing red phosphorus and near-infrared light
publisher KeAi Communications Co., Ltd.
series Bioactive Materials
issn 2452-199X
publishDate 2019-12-01
description Bone-implant materials are important for bone repairing and orthopedics surgery, which include bone plates and bone nails. These materials need to be designed not only considering its biostability and biocompatibility, but also their by-products induced infection after therapy or long-time treatment in vivo. Thus, the development of novel implant materials is quite urgent. Red phosphorus has great biocompatibility and exhibits efficient photothermal ability. Herein, a red phosphorus/IR780/arginine-glycine-asparticacid-cysteine (RGDC) coating on titanium bone-implant was prepared. The temperature sensitivity of Staphylococcus aureus biofilm is enhanced in the presence of ROS produced by IR780 with 808 nm light irradiation. With keeping the cells and tissues normal, a high antibacterial performance can be realized by near-infrared (808 nm) irradiated within 10 min at 50 °C. Besides the high effective antibacterial efficacy provided by photothermal therapy (PTT) and photodynamic therapy (PDT), the RGDC decorated surface can also possess an excellent performance in osteogenesis in vivo. Keywords: Implants, Red phosphorus, Near-infrared, Osteogenesis, Antibacterial, Biofilm
url http://www.sciencedirect.com/science/article/pii/S2452199X1830063X
work_keys_str_mv AT bohuang afacilefabricationofnovelstuffwithantibacterialpropertyandosteogenicpromotionutilizingredphosphorusandnearinfraredlight
AT leitan afacilefabricationofnovelstuffwithantibacterialpropertyandosteogenicpromotionutilizingredphosphorusandnearinfraredlight
AT xiangmeiliu afacilefabricationofnovelstuffwithantibacterialpropertyandosteogenicpromotionutilizingredphosphorusandnearinfraredlight
AT junli afacilefabricationofnovelstuffwithantibacterialpropertyandosteogenicpromotionutilizingredphosphorusandnearinfraredlight
AT shuilinwu afacilefabricationofnovelstuffwithantibacterialpropertyandosteogenicpromotionutilizingredphosphorusandnearinfraredlight
AT bohuang facilefabricationofnovelstuffwithantibacterialpropertyandosteogenicpromotionutilizingredphosphorusandnearinfraredlight
AT leitan facilefabricationofnovelstuffwithantibacterialpropertyandosteogenicpromotionutilizingredphosphorusandnearinfraredlight
AT xiangmeiliu facilefabricationofnovelstuffwithantibacterialpropertyandosteogenicpromotionutilizingredphosphorusandnearinfraredlight
AT junli facilefabricationofnovelstuffwithantibacterialpropertyandosteogenicpromotionutilizingredphosphorusandnearinfraredlight
AT shuilinwu facilefabricationofnovelstuffwithantibacterialpropertyandosteogenicpromotionutilizingredphosphorusandnearinfraredlight
_version_ 1724304117785952256

Similar Items