Three-Component Reactions of 3-Arylidene-3<i>H</i>-Indolium Salts, Isocyanides and Amines

Three-Component Reactions of 3-Arylidene-3<i>H</i>-Indolium Salts, Isocyanides and Amines

A multicomponent reaction of isocyanides with aryl(indol-3-yl)methylium salts and amines has been found. A series of aryl(indol-3-yl)acetimidamides was obtained in up to 96% yields. In the case of ethyl isocyanoacetate, the reaction is followed by cyclization to form 3,5-dihydro-4<i>H</i>...

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Bibliographic Details
Main Authors: Hung M. Nguyen, Nikita E. Golantsov, Alexandra S. Golubenkova, Victor B. Rybakov, Leonid G. Voskressensky
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Molecules
Subjects:
multicomponent reactions
isocyanides
carbenium ions
indoles
imidamides
imidazolones
Online Access:https://www.mdpi.com/1420-3049/26/9/2402
Description
Summary:A multicomponent reaction of isocyanides with aryl(indol-3-yl)methylium salts and amines has been found. A series of aryl(indol-3-yl)acetimidamides was obtained in up to 96% yields. In the case of ethyl isocyanoacetate, the reaction is followed by cyclization to form 3,5-dihydro-4<i>H</i>-imidazol-4-one derivatives.
ISSN:1420-3049

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