Prevention of Microsphere Blockage in Catheter Tubes Using Convex Air Bubbles

• Main Authors: Dong Hyeok Park, Yeun Jung Jung, Sandoz John Kinson Steve Jeo Kins, Young Deok Kim, Jeung Sang Go
• Format: Article
• Language: English
• Published: MDPI AG 2020-11-01
• Series: Micromachines
• Subjects: catheter; microspheres; blockage arching; convex air bubbles; slip; centrifugal
• Online Access: https://www.mdpi.com/2072-666X/11/12/1040

This paper presents a novel method to prevent blockages by embolic microspheres in catheter channels by using convex air bubbles attached to the channels’ inner wall surface. The clogging by microspheres can occur by the arching of the microspheres in the catheter. A few studies have been done on reducing the blockage, but their methods are not suitable for use with embolic catheters. In this study, straight catheter channels were fabricated. They had cavities to form convex air bubbles; additionally, a straight channel without the cavities was designed for comparison. Blockage was observed in the straight channel without the cavities, and the blockage arching angle was measured to be 70°, while no blockage occurred in the cavity channel with air bubbles, even at a geometrical arching angle of 85°. The convex air bubbles have an important role in preventing blockages by microspheres. The slip effect on the air bubble surface and the centrifugal effect make the microspheres drift away from the channel wall. It was observed that as the size of the cavity was increased, the drift distance became larger. Additionally, as more convex air bubbles were formed, the amount of early drift to the center increased. It will be advantageous to design a catheter with large cavities that have a small interval between them.