The Role of Wnt Pathway in the Pathogenesis of OA and Its Potential Therapeutic Implications in the Field of Regenerative Medicine
Introduction. Osteoarthritis (OA) is a degenerative joint disease characterized by articular cartilage degradation, subchondral damage, and bone remodelling, affecting most commonly weight-bearing joints, such as the knee and hip. The loss of cartilage leads to joint space narrowing, pain, and loss...
Main Authors: | Maria De Santis, Berardo Di Matteo, Emanuele Chisari, Gilberto Cincinelli, Peter Angele, Christian Lattermann, Giuseppe Filardo, Nicolò Danilo Vitale, Carlo Selmi, Elizaveta Kon |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2018-01-01
|
Series: | BioMed Research International |
Online Access: | http://dx.doi.org/10.1155/2018/7402947 |
Similar Items
-
Innovative Techniques to Enhance Musculoskeletal Surgery Outcomes
by: Berardo Di Matteo, et al.
Published: (2018-01-01) -
Wnt Signalling in Regenerative Dentistry
by: Anahid A. Birjandi, et al.
Published: (2021-08-01) -
The role of mechanical factors in the pathogenesis of murine OA
by: Burleigh, Annika
Published: (2010) -
PRP Augmentation for ACL Reconstruction
by: Luca Andriolo, et al.
Published: (2015-01-01) -
Regenerative Features of Adipose Tissue for Osteoarthritis Treatment in a Rabbit Model: Enzymatic Digestion Versus Mechanical Disruption
by: Giovanna Desando, et al.
Published: (2019-05-01)