MINDIN Exerts Protumorigenic Actions on Primary Prostate Tumors via Downregulation of the Scaffold Protein NHERF-1

MINDIN Exerts Protumorigenic Actions on Primary Prostate Tumors via Downregulation of the Scaffold Protein NHERF-1

Advanced prostate cancer preferential metastasis to bone is associated with osteomimicry. MINDIN is a secreted matrix protein upregulated in prostate tumors that overexpresses bone-related genes during prostate cancer progression. Na+/H+ exchanger regulatory factor (NHERF-1) is a scaffold protein th...

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Bibliographic Details
Main Authors: Luis Álvarez-Carrión, Irene Gutiérrez-Rojas, María Rosario Rodríguez-Ramos, Juan A. Ardura, Verónica Alonso
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cancers
Subjects:
NHERF-1
MINDIN
prostate cancer
bone
metastases
migration
Online Access:https://www.mdpi.com/2072-6694/13/3/436

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