PP2A mediated AMPK inhibition promotes HSP70 expression in heat shock response.

PP2A mediated AMPK inhibition promotes HSP70 expression in heat shock response.

BACKGROUND: Under stress, AMP-activated protein kinase (AMPK) plays a central role in energy balance, and the heat shock response is a protective mechanism for cell survival. The relationship between AMPK activity and heat shock protein (HSP) expression under stress is unclear. METHODOLOGY/PRINCIPAL...

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Bibliographic Details
Main Authors: Ting Wang, Qiujing Yu, Juan Chen, Bo Deng, Lihua Qian, Yingying Le
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2948495?pdf=render

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