Acute drug transfer and particle release of drug coated balloons within a porcine in-vitro model

Acute drug transfer and particle release of drug coated balloons within a porcine in-vitro model

Drug coated balloons (DCB) are used in the therapy of coronary as well as peripheral artery disease. The success of drug transfer to the vessel wall depends on the excipient used in combination with paclitaxel as antiproliferative drug. Although in-vivo studies show very good results with this techn...

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Bibliographic Details
Main Authors: Brandt-Wunderlich Christoph, Almstädt Lucas, Kaule Sebastian, Reske Thomas, Schmidt Wolfram, Schmitz Klaus-Peter, Grabow Niels
Format: Article
Language:English
Published: De Gruyter 2017-09-01
Series:Current Directions in Biomedical Engineering
Subjects:
drug coated balloon
drug transfer
in-vitro
paclitaxel
particulate evaluation
Online Access:https://doi.org/10.1515/cdbme-2017-0098

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